Trolamine salicylate: Indication, Dosage, Side Effect, Precaution

This information is not country-specific. Please refer to the Malaysia prescribing information.

Generic Medicine Info

Indications and Dosage

Topical/Cutaneous
Musculoskeletal pain

Adult: For temporary relief of minor aches and pains of muscles and joints associated with arthritis, simple backache, bruises, cramps, muscle strains and sprains: As cream, lotion, gel or spray: Apply liberal amount onto the affected area as needed up to 4 times daily. Massage treated area gently to enhance absorption. Refer to product-specific recommendations.
Child: >12 years Same as adult dose.

Contraindications

Hypersensitivity to trolamine salicylate, aspirin or other salicylates. Application on broken, inflamed or irritated skin.

Special Precautions

Children.

Adverse Reactions

Gastrointestinal disorders: Nausea, vomiting, diarrhoea.
Nervous system disorders: Confusion, drowsiness.
Respiratory, thoracic and mediastinal disorders: Hyperventilation.
Skin and subcutaneous tissue disorders: Skin irritation.

Patient Counseling Information

Do not bandage tightly or use with a heating pad. Avoid contact with eyes and mucous membranes.

Action

Description:
Mechanism of Action: Trolamine salicylate is a non-steroidal anti-inflammatory drug (NSAID) which is often used in topical rubefacient preparations in concentrations between 10-20%. It is believed to exert its action via a counter-irritant effect.
Pharmacokinetics:
Absorption: Rapidly and well absorbed after topical application.

Chemical Structure

Storage

Store between 20-25°C.

MIMS Class

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

References

Anon. Salicylate Salts. AHFS Clinical Drug Information [online]. Bethesda, MD. American Society of Health-System Pharmacists, Inc. https://www.ahfscdi.com. Accessed 04/07/2023.

Anon. Trolamine. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Accessed 04/07/2023.

Arthricream Cream (Kroger Company). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed. Accessed 04/07/2023.

Buckingham R (ed). Trolamine. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. https://www.medicinescomplete.com. Accessed 04/07/2023.

Dr Joe Lab Arthritis Extra Strength Cream (Despina Pharma Inc.). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed. Accessed 04/07/2023.

Dr Joe Lab Arthritis Extra Strength Gel (Despina Pharma Inc). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed. Accessed 03/11/2023.

Maximum Strength Blue Emu Pain Relief Blu Emu Spray (NFI, LLC). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed. Accessed 04/07/2023.

Trolamine Salicylate. Gold Standard Drug Database in ClinicalKey [online]. Elsevier Inc. https://www.clinicalkey.com. Accessed 03/11/2023.

Ultracin T Lotion (Cal Pharma). DailyMed. Source: U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed. Accessed 04/07/2023.

Disclaimer: This information is independently developed by MIMS based on Trolamine salicylate from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2024 MIMS. All rights reserved. Powered by MIMS.com